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KMID : 0378019810240110063
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New Medical Journal
1981 Volume.24 No. 11 p.63 ~ p.71
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Intravenous cholangiography using Meglumine iotroxinate (Biliscopin)
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Abstract
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A new intravenous cholangiographic agent, Meglumine iotroxinate (Biliscopin), is -eported as a most suitable contrast media.
Compared with other previously used. contrast media, it hold not only lower general toxicity from reduced binding to protein but also good radiographic visualization from maximum biliary transport rate and iodine concentration in the bile.
Biliscopin intravenous cholangiography was done in ?10 patients who was selected after Biligrafin study, 2 of normal cases, 2 of faint visualization, and 6 of nonvisuaization cases.
In serial films after injection, we compared the each group especially pay attention to the appearence time of common duct and gall bladder and its degree of opacification.
The results were as follows:
1. With Biliscopin, optimal visualization of bile duct was achieved 15 min. after injection, and GB was in 30 min. delay film. Bile duct and GB was opacified together in the 30-60min. film without further need of delay film.
2. Contast quality of bile duct and GB was better after Biliscopin injection than Biligrafin injection.
3. Among the 6 cases- who showed nonvisualization ;after Biligrafin injection from jaundice and hepatocellular dysfunction, 4 cases showed good opacification of bile duct after Biliscopin injection. Highest bilirubin level of the visualized cases after Biliscopin injection was 5.3mg%. Bilirubin level of the 2 nonvisualized cases ;even after Biliscopin injection was 5.4 and 7.lmg% respectively.
4. Visualization of the intrahepatic ducts was noted in one case after Biligrafin and 5 cases after Biliscopin injection.
5. 2 of the 10 cases showed: mild side reactions after Biligraf in injection, but there was any symptoms in these patients after Biliscopin injecton.
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